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The multi-campus facilities of Avera McKennan Hospital and University Health Center include: a network of primary and specialty clinics, Avera Behavioral Health Center, Avera Heart Hospital of South Dakota, Avera Living Well Center, Avera Prince of Peace long-term care and retirement community. The hospital's main campus includes the Avera Cancer Institute, Plaza 1, Plaza 2, Plaza 3 and Plaza 4, Avera Medical Group 7th Avenue, Avera Surgery Center, and the Center for Family Medicine.

A full service hospital and family medicine clinic located in the community of Chamberlain, SD. The facility provides acute, emergency, and medical care.

Featured health services include a Clinic, Hospital, Telehealth, Emergency Medical Services, Emergency Department, Primary Care, Surgery, Obstetrics, Radiology and Imaging, Laboratory, Respiratory Therapy, Cardiac Rehabilitation, Physical, Speech, and Occupational Therapy, Nutrition Services, Occupational Health Services, School Nurse Services, Diabetes Education, Diabetes Prevention Program, Hello, Baby! Education Series, Birthing Suites & Nursery, and CPR Classes.

Sanford Vermillion Medical Center is a full service hospital and clinic providing the following services: 24-Hour Emergency Care, Ground and Air Ambulance support/access, medical, surgical, pediatric, and obstetrical care, outpatient nursing services (including chemotherapy), family medicine clinic, diagnostic services, home care and hospice programs, outpatient mental health counseling, rehabilitation therapies, respiratory care, acute care hours Saturday morning, Sunday afternoon, and weekday evenings, sports medicine, community health education, specialty outreach services (cardiology, diagnostic radiology, ENT surgery, general surgery, neurology, nephrology, oncology, orthopedics, podiatry, psychiatry, pulmonology, urology, and vascular surgery), and University of South Dakota student health services. Vermillion Medical Center has a teaching affiliation with USD Health Science Program.

Featured health services include emergency and trauma, hospice, laboratory, nutrition, pain management, pharmacy, therapy and rehabilitation, radiology and imaging, respiratory and pulmonary care, sleep medicine, telemedicine, wellness care, preventive care, and women's health.

Featured health services include emergency and trauma, laboratory, radiology and imaging, medication disposal, surgical suite, physical and occupational therapy, and short stay observation.

Featured health services include diabetes and endocrinology, emergency and trauma, heart and vascular care, infectious disease and public health, laboratory, nutrition, pain management, pharmacy, radiology and imaging, respiratory and pulmonary care, sleep medicine, telemedicine, wellness and preventive care, women's health, and wound care.

A full service hospital and family medicine clinic providing acute, emergency, and medical care. This is also a medication disposal site.

LifeScape's Fisher Coon Unit is an 18-bed specialty hospital that offers post-acute care to patients from birth through age 21. The unit has two programs: Medically Complex and Inpatient Rehabilitation. Medically Complex Program This program is for patients with significant medical needs who do not require continuous acute care. The high nurse-to-patient ratio allows every child to receive individualized attention. Medically Complex Services IV therapy Nutritional therapy via gastrostomy, jejunostomy, NG or NJ Palliative care Respiratory therapy Tracheostomy care Skilled nursing observation following casting or surgeries Suctioning, oxygen administration Ventilator use and weaning Inpatient Rehabilitation Program This program serves children needing rehabilitation after accidents, illness, or surgery. Stays are typically short-term for intense rehabilitation to assist the patient in returning to their previous level of function.

A Critical Access Hospital equipped with medical/surgical, pediatric, intensive/coronary care, and swing bed/intermediate care. The Wagner Community Clinic is adjacent to the hospital making it convenient to see hospital patients, share laboratory services and other diagnostic equipment.

Featured health services include cancer care, blood diseases and disorders, brain and spine care, dentistry, emergency and trauma, heart and vascular care, infectious disease and public health, laboratory, nutrition, pain management, pregnancy and birth, Radiology and imaging, respiratory and pulmonary care, sleep medicine, surgery, telemedicine, therapy and rehabilitation, wellness and preventive care, women's health, and wound care.

Services include 45 bed hospital, emergency room, Obstetrics, Pediatrics, Surgical, Dental, and Prescription Assistance. Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS.

18-bed critical access hospital provides 24-hour emergency service, inpatient and outpatient care, ambulance service, home health care, laboratory services, physical therapy, and medication disposal.

Offers a complete health care facility providing in-patient and emergency care, lab and medical imaging, visiting specialists, physical, occupational, and speech therapy.

Services available include hospital (inpatient, outpatient and observation), swing bed (skilled nursing services), dietitian and nutrition services, rehabilitation services, laboratory services, X-ray and CT services, MRI, mobile mammogram and Dexa scan, clinic services, emergency services 24/7/365, telemental health, and various outreach services.

Featured health services include kidney care, emergency and trauma, home health, laboratory, pain management, pharmacy, therapy and rehabilitation, radiology and imaging, respiratory and pulmonary care, surgery, telemedicine, wellness and preventive care, women's health, and wound care.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Providing hospital services including ambulance, acute care, emergency room, swing bed, cardiac rehabilitation, and radiology. This is also a medication disposal site.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Medical complex with a hospital, resident nursing facility, and congregate housing apartments.

Provides a full range of healthcare services including: emergency services, therapy services (physical, occupational, and speech), cardiac rehab, hospice, inpatient care, laboratory services, radiology services, surgery, and wound care.

General medical and surgical, primary, nursing home, and rehabilitative care. Behavioral health services including addictive disorder services (ADS), compensated work therapy, Residential Post Traumatic Stress (PTSD) program, Mental health intensive case management, inpatient psychiatric services, and outpatient psychiatric services. Gun locks are available through the Suicide Prevention Coordinator.

COVID Testing Option: ​Oyate Health Center Urgent Care 3200 Canyon Lake Drive 7:00am - 7:00pm (MT), 7 days a week Christmas Eve closes at 3pm (MT). Closed on Thanksgiving Day, and Christmas Day and New Year's Day. Oyate Health Center provides primary medical care, outpatient clinic, and urgent care. Additional outpatient services that are provided on site include optometry, pharmacy (Prescription Drug Take Back Site, blue drop-box by pharmacy), laboratory, radiology, dental, physical therapy, podiatry, and social services. Oyate Health Center has 2 sweat lodges. Please call for details. Oyate Health Center provides direct health services to Native Americans and provides contract health care services and referrals to those that are eligible within IHS requirements. This means that if a patient is enrolled in a federally recognized tribe or can prove lineage of descent of an enrolled tribal member; the patient may receive direct care services at Oyate Health Center. Prescription Assistance - Any Native American enrolled in a federally recognized tribe can receive prescription expense assistance at any IHS facility.

Brookings Hospital is a licensed 49-bed hospital. Services include same day surgery/operating room, emergency room, inpatient care, obstetrics, and ancillary services - radiology, rehab/therapy, and laboratory. Full service hospital that provides both inpatient and outpatient care.

Provides the following services - emergency room, inpatient care, comprehensive primary care, Primary Care Medical Home (PCMH), behavioral health, adult and pediatric dental, eye clinic, radiology, laboratory, nursing, pharmacy, public health nursing, dietician, and telehealth (including behavioral health, internal medicine, and rheumatology).