An organization through which business owners, professionals, employees and citizens unite to provide leadership and direction for the economic and social development of our community. Partners benefit from the many programs and events held to promote their business and the business community as a whole.

The Vermillion Area Chamber & Development Company (VCDC) functions as a Chamber of Commerce, office of Economic Development, and Visitor/Tourism Bureau for Vermillion and the surrounding area. It operates in direct partnership with several other agencies, including the City of Vermillion, University of South Dakota, and the nonprofit Missouri Valley Growth, to better grow the economic prosperity of the area and create a positive environment in which to do business. Services include business counseling, member marketing, referrals, networking opportunities, ribbon cuttings, groundbreakings, and much more. The VCDC publishes a semi-annual newsletter informing community of business trends, area news, and new chamber members. The VCDC hosts a community events calendar at and an online business directory of organizations belonging to the chamber on the website.

An established voluntary non-profit 501c6 membership organization since 1884. Chamber volunteers can serve on eight different committees that focus efforts on programs that support community growth and development. Each address different community and business issues and opportunities. Some programs include Leadership Aberdeen, Aberdeen Gift Card, Chamber for Good and Mental Wellness in the Workplace, just to name a few. An online business directory of organizations belonging to this chamber is available on the website.

The Huron Chamber & Visitors Bureau serves members by strengthening business, supporting visitors and enhancing community. An online business directory of organizations belonging to this chamber and a community calendar of events is available on website.

Citizens can contact the City of Harrisburg main office regarding the following: register for utility services, obtain building permits, planning and zoning inquiries, register pets, pay utility bills, notary services, economic development and Harrisburg chamber information, liquor licenses, garbage licenses, and peddler licenses. An online business directory of organizations belonging to this chamber is available on website.

The Chamber of Commerce plans events, answers questions about Sisseton, and promotes local businesses.

Promotes and protects the interests of its members in many ways including hosting local events and working to increase traffic into the town.

Promotes the community with marketing and advertising in several tourist publications each year. The Chamber also hosts several events through the year including Winterfest, Gold Camp Jubilee: A 4th of July Celebration Black Hills Renaissance Festival, and Fall In Love With Lead. Events calendar and an online business directory of organizations belonging to the chamber is available on the website.

Services include tourism marketing, visitor information, business assistance, event planning for the community, agriculture program, advocacy, online business directory of organizations belonging to this chamber, and events calendar can be found on website.

Partnership of business and professional people working together for the betterment of the community. Services include community event planning, tourism services, marketing, and business services.

Promotes the commercial, industrial, civic, and general interests for members of the Chamber of Commerce, the City of Belle Fourche, and its trade area. The Chamber provides answers to questions, professional development opportunities, and networking opportunities.

Advocates for the Britton Area business community and promotes economic development. Represents business interests to local, state, or federal governments. Encourages and supports the growth of businesses, job creation, and regional prosperity. Facilitates connections and partnerships among local businesses and fosters community involvement. Provides resources such as professional development, marketing opportunities, and businesses tools to members. Ensures long-term growth and sustainability for both businesses and the community.

The Chamber serves as a welcome, information and resource center for the entire Dell Rapids area. An online directory of organizations and events calendar can be found on website. 

Dedicated to promoting Hill City's community growth and sustainability; strengthening economic and social environments; serving needs of members and community; and cooperating with civic leaders, community organizations, and neighboring communities.

Provides Information, communication, events, and business opportunities in the Custer Area. Also provides listings of area clubs, organizations, businesses, and tourist information. Events calendar and an online business directory of organizations belonging to this chamber can be found on the website.

Yankton Thrive is made up of small and large businesses interested in prospering and creating a healthy environment in which to conduct business. Yankton Thrive offers and supports a variety of events and programs in the community including community advocacy, business and career expo, business resources and seminars, holiday promotions, leadership programs, ribbon cuttings, and information on community child care providers and after school programs. An online business directory of organizations belonging to Yankton Thrive are available on website.

Promotes the Arlington area local economy and businesses through marketing initiatives, resources, and events. Connects community members through networking events, monthly meetings, and collaborative projects.

The Chamber plays a role in helping make the community a better place to live. A group of local businesses and residents meet throughout the year to demonstrate commitment to building and maintaining a prosperous community, for those who live there, and for those who may visit or pass through Clear Lake. The goal of the CLCC is to promote and advance the economic, social and moral interest of its businesses and community through strong leadership, networking, education and hard work by its members and other vested community residents. ​

Provides networking opportunities for the business owners of Centerville, inclusion on the Chamber Website and social media posts. A membership provide opportunities to promote businesses, support and facilitate community events, as well as invest back into the community.

Helps start up businesses and provide educational classes. Also offers business classes in Spanish.

Advocates on behalf of its members and actively supports business, agriculture and tourism resulting in an enhanced quality of place for the entire community, services include: Visitor information Relocation information Sturgis Rally information Community support and advocacy Leadership training An online business directory of organizations belonging to this chamber is available on website.

A statewide business organization whose goal is to improve and work for the betterment of business and industry in South Dakota. Sponsors the following: Business Day at the Legislature, Economic Outlook Seminar, and Giant Vision Startup Competition. An events calendar and online business directory belonging to the chamber at this time is available on the website.

Promotes community to ensure growth and stability for Canton businesses. An online business directory of organizations belonging to this chamber is available on the website.

Promotes the business and economic interests of the Alcester area. Representatives from member businesses meet to promote the economic, professional, educational, cultural, and civic welfare of the Alcester area.

Offers a variety of programming and events, including but not limited to - Downtown at Sundown summer concert series, Young Professionals Network, Women in Leadership Luncheons, Veterans Day Program, New Resident Welcome programming, SDSU student engagement, advocacy, Leadership Brookings, professional development opportunities, and networking events.