Huron Clinic is a Family Medicine clinic, providing medical services to patients in Huron and the surrounding area. Services include Vaccinations and flu shots: adult and childhood immunizations, Family medicine, Routine physicals: annual, school, pre-employment, work, and DOT certified exams, Allergy and immunization: therapeutic injections, and allergy shot administration, Women's health: pap tests, breast screening, contraception, and STI/STD testing, Screening: in-house laboratory testing, bone density, cancer, diabetes, cholesterol, drug, alcohol, vision, and hearing. Cardio health: EKG and blood pressure screening, Pulmonary health: nebulizer treatments, pulmonary function testing, Diabetes: screening, education, diet information, weight management, and medication management, Minor surgery: mole/lesion removal, laceration repair, skin tag removal, wart removal, and liquid nitrogen treatment, Joint injections and aspirations: cortisone injections and fluid removal, Skin Cancer Screening, and Imaging: x-rays, ultrasound, and bone density testing.

Services for the clinic include family medicine, family planning, geriatric medicine, pediatrics, lab services, podiatry, pediatrics, preventative medicine, physical exams for women and children, and X-ray services.

Avera Medical Group McGreevy clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services including regular check-ups or vaccines, plus care for injuries and illnesses.

Sanford Health Pierre Clinic offers health care services for patients of all ages.

Sanford Health's family medicine clinics provide care for the whole family - from babies to grandparents. Treats a variety of illnesses and injuries; from annual physicals, regular checkups, baby wellness, vaccinations and school and athletic physicals.

Services include obstetrics with ultrasound, delivery with intrathecal block, pediatrics with inhalation therapy and IV therapy, family practice, geriatrics, disease management, hormone replacement therapy, and 24-hour emergency care and outpatient hospital.

The programs offered by this agency include community organizing and leadership development, AIDS Prevention program, Child Development program, Adult learning program, Environmental issues, Transitional housing, Cancer prevention, Fetal Alcohol Syndrome awareness program, Clearinghouse of health educational materials, Newsletter, Dakota Talk Radio, KDKO Radio 89.5 FM, diabetic nutrition program, scholarships for Native American women, women's reproductive health programs, Food Sovereignty, and community health events.

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

Services include cancer services/oncology, cardiology, chaplain services, diabetes care, diagnostic imaging, emergency and trauma care, home health and hospice, home medical equipment, occupational health, orthopedics, pediatrics, rehabilitation services, senior services, sports medicine, telemedicine, wellness services, women's specialty services, and family medicine.

Acute Care offers after hours and weekend care for those medical needs that can't wait but do not require the services of an Emergency Department. An M.D. is always present during Acute Care hours. Walk-in care for urgent care needs, such as fevers, flu, sprains, and more.

Avera Medical Group McGreevy clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services including regular check-ups or vaccines, plus care for injuries and illnesses.

Offering compassionate and comprehensive care for all patients. Services include annual physicals, immunizations, medication management, transitional care management, joint injections, lesion/wart removal, splinting/casting, and Behavioral Health appointments via telehealth. Same Day Appointments are available during regular business hours Monday to Friday as well as Urgent Care appointments on Saturdays.

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

Avera Medical Group McGreevy clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services including regular check-ups or vaccines, plus care for injuries and illnesses.

Stepping Into Good Health (SIGH) is a project that works with Falls Community Health to ensure that men and women find an open door to healthcare services such as foot care (toenail trimming, buffing, massage, and a new pair of socks), health education and screening, and spiritual support (staffed by a faith community nurse, a certified foot care nurse).

General medical and surgical, primary, nursing home, and rehabilitative care. Behavioral health services including addictive disorder services (ADS), compensated work therapy, Residential Post Traumatic Stress (PTSD) program, Mental health intensive case management, inpatient psychiatric services, and outpatient psychiatric services. Gun locks are available through the Suicide Prevention Coordinator.

A satellite clinic for the Philip Health Services clinic providing general health care to the community. Provider staffing may be limited; clinic nurses may be able to assist patients.

Medical services provided include: adult medicine, women's health, obstetrics, pediatric medicine, physicals, wound care, minor surgeries, radiology, laboratory, disease management, rehabilitation and therapy services, and cardiology, podiatry, orthopedics, surgery outreach services.

A primary care and family medicine clinic.

Acute Care offers after hours and weekend care for those medical needs that can't wait but do not require the services of an Emergency Department. An M.D. is always present during Acute Care hours. Walk-in care for urgent care needs, such as fevers, flu, sprains, and more.

A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adult, and geriatric patients. Services include preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, radiology, and lab services.

Providing clinical health services for all ages, including Medication-Assisted Treatment, senior care, maternity, pediatric, men's health, LGBTQ+ care, vaccinations, lab services, and telehealth visits. A Community Health Worker is also available to help coordinate services.

Sanford Vermillion Medical Center is a full service hospital and clinic providing the following services: 24-Hour Emergency Care, Ground and Air Ambulance support/access, medical, surgical, pediatric, and obstetrical care, outpatient nursing services (including chemotherapy), family medicine clinic, diagnostic services, home care and hospice programs, outpatient mental health counseling, rehabilitation therapies, respiratory care, acute care hours Saturday morning, Sunday afternoon, and weekday evenings, sports medicine, community health education, specialty outreach services (cardiology, diagnostic radiology, ENT surgery, general surgery, neurology, nephrology, oncology, orthopedics, podiatry, psychiatry, pulmonology, urology, and vascular surgery), and University of South Dakota student health services. Vermillion Medical Center has a teaching affiliation with USD Health Science Program.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Avera Medical Group McGreevy clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services including regular check-ups or vaccines, plus care for injuries and illnesses.