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Providing clinical health services for all ages, including Medications for Opioid Use Disorder, senior care, maternity, pediatric, men's health, LGBTQ+ care, vaccinations, lab services, and telehealth visits. A Community Health Worker is also available to help coordinate services.

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Providing general and specialized medical care and occupational services. Acute care services.

Offer's women's health services such as annual exams, maternity care, radiology & imaging, and laboratory tests.

A multi-specialty health care clinic with a variety of specialties such as: cardiology; family practice; pediatrics; radiology; urology; orthopedics; general surgery; internal medicine; OB/GYN; palliative medicine; geriatric medicine; full service laboratory; pulmonology; nephrology; rheumatology; physical medicine; and diagnostic imaging center.

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

Medical services include: Family medicine Obstetrics and gynecology Pediatrics Acute care Orthopedics and sports medicine 3D mammography Cardiology - adult and pediatric Certified nurse midwife Ear, nose and throat Pulmonology Vascular surgery Weight loss management Behavioral health counseling provides brief therapy for individuals, including mental health assessment, crisis intervention and referrals for children, couples and families. Psycho-social support for individual with chronic or newly diagnosed health conditions and wellness support.

Surgery (24-bed specialty hospital) and specialty care in orthopedics, internal medicine, rheumatology and urogynecology. Avera Human Performance Center focuses on the needs of people who want to improve their overall physical performance or recover from injuries through sports medicine, orthopedic, therapy, and sports performance training services. This location is also home to the Avera Addiction Care Center which features residential care for adults seeking treatment of alcohol or drug addiction.

Wall Monument Medical Clinic is a primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Services include Family medicine, Electrocardiogram, Laboratory, and Medical imaging.

Services include obstetrics with ultrasound, delivery with intrathecal block, pediatrics with inhalation therapy and IV therapy, family practice, geriatrics, disease management, hormone replacement therapy, and 24-hour emergency care and outpatient hospital.

Providing healthcare services for all women through all stages of your life. Services include ultrasound, colposcopy, gynecological surgery, genetic counseling for breast cancer and ovarian cancer, and biopsies for cancer screening.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, the Browns Valley Clinic in Browns Valley, Minnesota, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), and Women's Health. The take-back site is available.

Medical services that are offered include allergy, asthma, and immunology, dermatology, ear, nose, and throat, family medicine, gastroenterology, general surgery, internal medicine, interventional pain, obstetrics and gynecology, ophthalmology, optometry, pediatrics, podiatry, and rheumatology.

Offers the following services: primary care, birth control, morning-after pill (emergency contraception), breast and chest exams including mammogram referrals if necessary, HIV testing, LGBTQ Services, men's health care, pregnancy testing and services, STD testing/treatment/vaccines, women's health care, gender affirming hormone therapy (GAHT), HPV vaccinations, Hepatitis B vaccinations, and Flu shots. Telehealth visits are available on Tuesdays for some of these services.

Provides family medicine, OB/GYN, pediatrics, behavioral health, and mammography.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Bison Clinic is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

A full service hospital level one trauma with 24-hour emergency care. Offers acute care services including Cardiology, Oncology, Obstetrics, Orthopedics, sleep disorder center, inpatient and outpatient surgery, rehabilitative services, and comprehensive services for women and children.

Medical services that are offered include allergy, asthma, and immunology, dermatology, ear, nose, and throat, family medicine, gastroenterology, general surgery, internal medicine, interventional pain, obstetrics and gynecology, ophthalmology, optometry, pediatrics, podiatry, and rheumatology.

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Horizon Health - Aberdeen is full-service medical clinic offering the following services -preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

A primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs. Services include Family medicine, Bone density screening, BOTOX® cosmetic rejuvenation, Concussion management, Glycolic facial peels, Laboratory, Occupational therapy, Office-based surgery, Physical therapy, Speech therapy, and X-ray.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Offers: urgent care, 24-hour emergency room, family practice, OB/GYN, pediatrics, optometry, occupational medicine, and mammography.