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A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adult, and geriatric patients. Services include preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, radiology, and lab services.

Horizon Health - White River is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides emergency care, pediatrics, family medicine, general practice medicine, inpatient and outpatient rehabilitation therapy, medical imaging, OBGYN, 3D mammography (Free mammogram and cancer screening program 'We've Got You Covered'), chemotherapy, laboratory services, internal medicine, general surgery, dialysis, home health, hospice, intensive care, outpatient treatment, same day surgery, orthopedic surgery, podiatric surgery, prenatal care, and swing bed.

Providing a range of generalized and specialized services including a Sleep Center, Surgical Services, Pain Management, and Sports Medicine.

Services include audiology, purchased referred care, dietitians, emergency department, eye care, pharmacy, physical therapy, public health nursing, radiology services, pain management, OB/GYN, prenatal care, inpatient care, laboratory, Magnetic Resonance Imaging (MRI), medicine, and nursing.

Services including: primary and secondary care, adult day services, behavioral health, maternal, pregnancy, and birthing center, cancer detection care, chronic pain, dialysis, emergency care, heart care, home care, hospice, intensive care unit, mammography, MRI, OB/GYN, radiology, sleep disorders, surgery, and wellness center.

Horizon Health - Wessington Springs Medical is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Wessington Springs Dental provides a full range of family oral health services including preventative care (check ups, fillings), restorative and cosmetic dentistry (crowns, bridges) , endodontics, and oral surgery (root canals, extractions).

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

Offers women's health services such as annual exams, personalized maternity care, ultrasound, laboratory tests, home-delivered specialty medications, radiology and imaging, and childbirth education classes.

Medical services that are offered include allergy, asthma, and immunology, dermatology, ear, nose, and throat, family medicine, gastroenterology, general surgery, internal medicine, interventional pain, obstetrics and gynecology, ophthalmology, optometry, pediatrics, podiatry, prenatal care, and rheumatology.

A primary care, family medicine clinic that provides comprehensive care for the entire family through all phases of life, from childhood to senior years. Board certified physicians and physician assistants offer health care services sensitive to individual needs. Services include: outpatient counseling for adults and adolescents, family medicine, audiology/hearing aids, bone density screening, childhood & adult immunizations, general surgery, laboratory, OB/GYN, office-based surgery, sports & pre-employment physicals, and x-ray.

The Family Medicine Residency Clinic provides comprehensive care for the entire family in all phases of life, from childhood to senior years. Services include care for acute and chronic medical problems, care for expectant moms, well-baby visits and immunizations, school sports physicals, OB/GYN, prenatal care, annual check-ups, immunizations, and minor surgical procedures.

A medical clinic offering family medicine, obstetric and general surgery services.

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

Offer's women's health services such as annual exams, maternity care, prenatal care, radiology & imaging, and laboratory tests.

Providing the following medical services: Adult Medicine - annual checkups, wellness consultations, comprehensive evaluations, preventative care, and diagnostic services. Women's Health - annual health exams, pap smears, breast health services, and routine gynecological care. Obstetrics - prenatal and postpartum care in partnership with OB/GYN specialists. Pediatric Medicine - well-child visits, immunizations Minor Surgery - laceration repair, foreign body removal, wart removal, biopsies (skin or superficial lesions), excision of ingrown toenails, fractures and sprain care. Radiology - digital x-rays, CT whole body scans, MRI's, ultrasounds, DXA (Bone Density & Total Body Composition), Digital 3D Mammography, nuclear medicine, EKG's. Disease Management - can help monitor conditions such as hypertension, thyroid disease, diabetes, cardiac conditions, etc. Rehabilitation/Therapy Services - physical therapy, occupational therapy, speech therapy. Specialty Outreach Services - cardiology, podiatry, orthopedics, surgery.

Horizon Health - De Smet Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Located on the Pine Ridge Reservation, it is an ambulatory care center with outpatient services. Services include primary care, pediatric, women's health, optometry, dental, behavioral health, podiatry, radiology, and laboratory tests.

A primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Specialties include family medicine, internal medicine, childhood and adult immunizations, and sports and pre-employment physicals.