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An independent, nonprofit critical access hospital providing the following services: emergency care, cardiac rehabilitation services, coronary care, diabetes counseling, intensive care, in-patient services, obstetrics/childbirth services, occupational therapy, physical therapy, pulmonary care services, radiology services, respiratory therapy, sleep studies, swing bed program, surgical services, and on-site specialty providers (orthopedics, pain management, cardiology, urology, and audiology).

Full service hospital, including clinic and assisted living facility, ambulance, ER.

Featured health services include a Clinic, Hospital, Telehealth, Emergency Medical Services, Emergency Department, Primary Care, Surgery, Obstetrics, Radiology and Imaging, Laboratory, Respiratory Therapy, Cardiac Rehabilitation, Physical, Speech, and Occupational Therapy, Nutrition Services, Occupational Health Services, Prenatal Care, School Nurse Services, Diabetes Education, Diabetes Prevention Program, Hello, Baby! Education Series, Birthing Suites & Nursery, and CPR Classes.

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

Provides prenatal care and delivery care to families who do not have insurance or Medicaid coverage for their pregnancy. The program is income based.

Featured health services include cancer care, blood diseases and disorders, brain and spine care, dentistry, emergency and trauma, heart and vascular care, infectious disease and public health, laboratory, nutrition, pain management, pregnancy and birth, Radiology and imaging, respiratory and pulmonary care, sleep medicine, surgery, telemedicine, therapy and rehabilitation, wellness and preventive care, women's health, and wound care.

Providing general and specialized medical care and occupational services. Acute care services.

Clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Horizon Health - Elk Point is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Providing care for residents in the Clark community. Services include annual physicals, baby wellness checks, prenatal care, regular checkups, school and athletic physicals, internal medicine, and vaccinations.

Surgery (24-bed specialty hospital) and specialty care in orthopedics, internal medicine, rheumatology and urogynecology. Avera Human Performance Center focuses on the needs of people who want to improve their overall physical performance or recover from injuries through sports medicine, orthopedic, therapy, and sports performance training services. This location is also home to the Avera Addiction Care Center which features residential care for adults seeking treatment of alcohol or drug addiction.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

A full service hospital and family medicine clinic located in the community of Chamberlain, SD. The facility provides acute, emergency, and medical care.

The VA Surgery / Specialty Care Service Line includes the following services: Orthopedics, ENT, Gynecology, Urology, general surgery, Opthalmology, Podiatry, Audiology, Optometry, Dental, GI Endoscopy, and Proctology.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Sanford Health's family medicine clinics provide care for the whole family - from babies to grandparents. Treats a variety of illnesses and injuries; from annual physicals, regular checkups, baby wellness, vaccinations and school and athletic physicals as well as offering OB/GYN and prenatal care.

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

The Avera Medical Group Gregory is a member of the Avera McKennan Primary Care Network and Avera Health. Services include children's health, pregnancy and birth, primary care, urgent care, and women's health.

Offers women's health services such as annual exams, personalized maternity care, ultrasound, laboratory tests, home-delivered specialty medications, radiology and imaging, and childbirth education classes.

Services include audiology, purchased referred care, dietitians, emergency department, eye care, pharmacy, physical therapy, public health nursing, radiology services, pain management, OB/GYN, prenatal care, inpatient care, laboratory, Magnetic Resonance Imaging (MRI), medicine, and nursing.

Offers women's health services such as annual exams, personalized maternity care, ultrasound, laboratory tests, home-delivered specialty medications, radiology and imaging, and childbirth education classes.

Clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Providing the following medical services: Adult Medicine - annual checkups, wellness consultations, comprehensive evaluations, preventative care, and diagnostic services. Women's Health - annual health exams, pap smears, breast health services, and routine gynecological care. Obstetrics - prenatal and postpartum care in partnership with OB/GYN specialists. Pediatric Medicine - well-child visits, immunizations Minor Surgery - laceration repair, foreign body removal, wart removal, biopsies (skin or superficial lesions), excision of ingrown toenails, fractures and sprain care. Radiology - digital x-rays, CT whole body scans, MRI's, ultrasounds, DXA (Bone Density & Total Body Composition), Digital 3D Mammography, nuclear medicine, EKG's. Disease Management - can help monitor conditions such as hypertension, thyroid disease, diabetes, cardiac conditions, etc. Rehabilitation/Therapy Services - physical therapy, occupational therapy, speech therapy. Specialty Outreach Services - cardiology, podiatry, orthopedics, surgery.

Sanford Health's family medicine clinics provide care for the whole family - from babies to grandparents. Treats a variety of illnesses and injuries; from annual physicals, regular checkups, baby wellness, vaccinations and school and athletic physicals as well as offering OB/GYN and prenatal care.