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Horizon Health - Faith is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Faith is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

Horizon Health - Huron is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, prenatal care, patient education, care management, DOT exams, immigration physicals, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Horizon Health - Huron also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Spanish and Karen translators available on-site.

Sanford Health's family medicine clinics provide care for the whole family - from babies to grandparents. Treats a variety of illnesses and injuries; from annual physicals, regular checkups, baby wellness, vaccinations and school and athletic physicals as well as offering OB/GYN and prenatal care.

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

Sanford Vermillion Medical Center is a full service hospital and clinic providing the following services: 24-Hour Emergency Care, Ground and Air Ambulance support/access, medical, surgical, pediatric, and obstetrical care, outpatient nursing services (including chemotherapy), family medicine clinic, diagnostic services, home care and hospice programs, outpatient mental health counseling, rehabilitation therapies, respiratory care, acute care hours Saturday morning, Sunday afternoon, and weekday evenings, sports medicine, community health education, specialty outreach services (cardiology, diagnostic radiology, ENT surgery, general surgery, neurology, nephrology, oncology, orthopedics, podiatry, psychiatry, pulmonology, urology, and vascular surgery), and University of South Dakota student health services. Vermillion Medical Center has a teaching affiliation with USD Health Science Program.

A full service hospital and family medicine clinic located in the community of Aberdeen, SD. The facility provides acute, emergency, and medical care, full lab, with diagnostic testing, outpatient infusion, respiratory therapy, radiology, rehabilitation, diabetes care, pharmacy, flu shots, surgery, women's center/labor and delivery, oncology/cancer, and cardiology/heart.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Sanford Health's family medicine clinics provide care for the whole family - from babies to grandparents. Treats a variety of illnesses and injuries; from annual physicals, regular checkups, baby wellness, vaccinations and school and athletic physicals as well as offering OB/GYN and prenatal care.

Providing general and specialized medical care and occupational services. Acute care services.

A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adults, and geriatric patients. Offers preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, women's health care, radiology, lab services, and mental/behavioral health services.

A full service hospital and family medicine clinic providing acute, emergency, and medical care. This is also a medication disposal site.

Featured health services include Avera QuickLabs, emergency and trauma, pharmacy, therapy and rehabilitation, pregnancy and birth, prenatal care, OB/GYN, radiology and imaging, respiratory and pulmonary care, sleep medicine, telemedicine, urgent care, urology, wellness and preventive care, women's health, and wound care.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Featured health services include kidney care, cancer care, blood diseases and disorders, brain and spine care, dentistry, diabetes and endocrinology, emergency and trauma, heart and vascular care, infectious disease and public health, laboratory, nutrition, pain management, pharmacy, medication disposal, therapy and rehabilitation, pregnancy and birth, radiology and imaging, respiratory and pulmonary care, sleep medicine, surgery, telemedicine, wellness and preventive care, women's health, and wound care.

Rural Health Clinic provides primary care including family medicine and ancillary services. Board Certified Physicians and Nurse Practitioners tailor health care services to each individual's needs. Services include family medicine, family wellness exams, fracture care, geriatric care, minor surgical procedures, pediatric care, prenatal/gynecology, and vaccinations.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

A medical clinic offering family medicine, obstetric and general surgery services.

An ambulatory care center with outpatient services. Services include dental care, mental health services, public health nurse, environmental health care, optometry, laboratory, radiology, pharmacy (Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS), podiatry, HIV Clinic, SANE services, and Fitness Center.

Provides a variety of services including patient care, diagnostic services, support services, chemotherapy, emergency department, heart health, Planet Heart vascular and heart screening, nursing service, maternity care, medical/surgical, newborn nursery, pediatrics, respite care, swing bed, outpatient treatment, pain management, pregnancy and childbirth, rehabilitation services, cardiac rehab, occupational therapy, physical therapy, speech therapy, sleep study lab, surgical procedures, and telehealth.

Sponsored by Avera, Avera St. Luke's facilities include a hospital and comprehensive retirement communities in Aberdeen and Eureka, and clinics. Services include: addiction care (residential and outpatient services), behavioral health services (inpatient and outpatient), cancer services/medical oncology and radiation oncology, cardiology, dermatology, diabetes care, diagnostic imaging, emergency and trauma care, home health and hospice, Human Performance Center, hyperbaric oxygen treatments (wounds only), kidney dialysis, long-term care, nephrology, OB/GYN, occupational health, orthopedics, pain management, pediatrics, physical medicine and rehab, podiatry, primary care (family practice and internal medicine), prenatal care, primary care clinic (Groton, SD, and Ellendale, ND), pulmonology, same-day sick visit clinic, sleep lab, spine surgery, surgery, after-hours clinic, urology, wellness services, women's specialty services, and wound care.

Horizon Health - Elk Point is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Horizon Health - Mission is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, prenatal care, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides obstetrical and gynecologic care (OB/GYN) and surgical services for women in Western South Dakota. Services include breast exam, colposcopy, hysteroscopy, routine and high-risk obstetrical care, in-office lab services, laparoscopy, menopause treatment, pap smear and HPV, permanent sterilization, prenatal care, routine well woman care, sexually transmitted infections, ultrasound exam, and urinary incontinence.

Provides care to people of all sexes and gender identities on a sliding fee scale. Confidential birth control services including birth control pills and injections (donations only or sliding scale charge). Physical exams, pap-tests, exams/testing and treatment for sexually transmitted infections (male and female patients including teens), information about all forms of birth control, infertility information and referral, pregnancy diagnosis and referrals.